N-乙间甲苯胺是制备彩色胶卷的显影套药CD-2,CD-3,CD-4和高档酸性染料,分散染料的重要中间体。它的制备与合成主要有:气相法、中压液相法、溴乙烷法和磷酸二乙酯法。这些合成方法各有优点与不足。用硫酸二乙酯合成N-基间甲苯胺尚未见有文献报道。硫酸二乙酯是一种较常用的乙基化试剂,可是它的反应活性比较高,容易生成N,N-二乙基芳胺,因此一般把它用作仲胺的乙基化试 N-ethyl-toluidine is the preparation of color film developing sets of drugs CD-2, CD-3, CD-4 and high-grade acid dyes, disperse dyes important intermediates. Its preparation and synthesis are: gas phase method, medium pressure liquid phase method, ethyl bromide method and diethyl phosphate method. Each of these methods has its advantages and disadvantages. Synthesis of N-methyl-toluidine with diethyl sulfate has not been reported in the literature. Diethyl sulfate is a more commonly used ethylating agent, but its reactivity is relatively high and it is easy to form N, N-diethylarylamine. Therefore, it is generally used as an ethylamine test for secondary amines