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目的比较步长脑心通胶囊和拜阿司匹林在缺血性卒中二级预防中的疗效。方法将120例缺血性卒中患者随机分成两组:脑心通组口服步长脑心通胶囊4粒/次,2次/d;拜阿司匹林组口服拜阿司匹林片1片(100mg),每晚1次,随访2年,比较治疗前后血液流变学指标,血脂各项指标的变化情况;复发性脑卒中的发生率;药物的副反应及依从性。结果步长脑心通组明显改善了血液流变学、血脂各项指标;复发性脑卒中的发生率低;药物的副反应少,依从性好。结论步长脑心通胶囊在缺血性卒中二级预防中的疗效优于拜阿司匹林,而出血事件的发生率低。
Objective To compare the curative effect of stephennaoxutong capsule and aspirin on secondary prevention of ischemic stroke. Methods One hundred and twenty patients with ischemic stroke were randomly divided into two groups: Naoxintong group was given Buxusongpitong capsule 4 tablets / time, twice a day, while aspirin group was given 1 tablet of Aspirin tablets (100mg) 1 times, followed up for 2 years, before and after treatment to compare the changes of blood rheology indicators, blood lipid indicators; the incidence of recurrent stroke; drug side effects and compliance. The results of step Naoxintong group significantly improved hemorheology, blood lipid indicators; the incidence of recurrent stroke is low; drug side effects, compliance is good. Conclusion Bu Tong Naoxintong capsule in the secondary prevention of ischemic stroke better than aspirin, and the incidence of bleeding is low.