论文部分内容阅读
恶性肿瘤是严重危害人类健康的疾病,目前对恶性肿瘤的治疗主要依靠外科手术、化疗和放疗。有关调查显示:在恶性肿瘤患者最关心的十大问题中,呕吐、恶心占前两位。化疗和放疗引起恶心和呕吐的机理,是由于化、放疗作用于胃肠道的粘膜组织,从而使胃肠的类嗜铬细胞释放多巴胺及5-羟色胺(5-HT),这些神经递质与5-HT_3受体结合,通过神经反射作用到呕吐中枢,引起恶心、呕吐。严重的呕吐、恶心会引起一系列的问题,给患者的体质及精神带来极大的负面影响。增加了医护人员的工
Malignancy is a serious disease that endangers human health. At present, the treatment of malignant tumors mainly depends on surgery, chemotherapy and radiotherapy. The survey shows: Among the top ten issues most concerned about by cancer patients, vomiting and nausea accounted for the top two. Chemotherapy and radiotherapy cause nausea and vomiting mechanism is due to chemotherapy, radiotherapy in the gastrointestinal mucosa, so that gastrointestinal class of chromaffin cells release dopamine and serotonin (5-HT), these neurotransmitters and 5-HT_3 receptor binding, through the reflex effect to the vomiting center, causing nausea and vomiting. Severe vomiting, nausea can cause a series of problems, the patient’s physique and spirit have a tremendous negative impact. Increase the work of medical staff