食管静脉曲张出血通常发生在食管最下端2cm 处,此处被食管下括约肌(LOS)所围绕。1978年Mis-kowiak 提出用药物收缩LOS 可能影响曲张静脉内的血流,门脉造影显示其中的血流减少或消失,而食管旁静脉中的血流则不受影响。作者等对11例食管静脉曲张患者进行试验研究。这些患者过去未接受过任何治疗。在经内镜做硬化剂注射治疗时,先测食管内和曲张静脉内的压力,然后静脉 Esophageal varices usually occur at the lowermost 2 cm of the esophagus, surrounded by the lower esophageal sphincter (LOS). In 1978, Mis-kowiak proposed that drug constriction of LOS may affect blood flow in varicose veins, which shows reduced or absent blood flow, whereas blood flow in the paraesophageal vein is unaffected. The authors of 11 cases of esophageal varices in patients with experimental study. These patients have not received any treatment in the past. In endoscopic sclerotherapy injection, the first measure intra-and varicose vein pressure, and then intravenous