肾脏疾病和许多全身性疾病,均可影响肾脏血液循环。研究肾脏循环和微循环,对于阐明发病机理和治疗机制,是相当重要的。目前国内外测量肾动脉血流量,较普遍应用的方法是电磁流量计,不太常用的有同位素廓清和提取等方法。但是电磁流量计不能测量肾脏局部血流量,同位素廓清及提取方法不能做连续测量。近几年,国外发展了一项放射性塑料微球技术,可以连续地测量全部和局部(肾皮质内、外层、髓质)肾血流量,弥补了上述方法的不足,为研究肾脏微循环提供了有利条件。虽然微球技术的应用,使国外理论工作著,在肾脏微循环研究方面, Kidney disease and many systemic diseases can affect kidney blood circulation. Studying kidney circulation and microcirculation is quite important for elucidating the pathogenesis and treatment mechanisms. Current measurement of renal artery blood flow at home and abroad, the more common method is to use electromagnetic flowmeter, less commonly used methods such as isotope clearance and extraction. However, the electromagnetic flowmeter can not measure the local renal blood flow, isotope clearance and extraction methods can not do continuous measurement. In recent years, foreign countries have developed a radioactive plastic microspheres technology, continuous measurement of all and local (renal cortex, outer layer, medulla) renal blood flow, make up for the lack of these methods for the study of renal microcirculation The favorable conditions. Although the application of microspheres technology, so that the theory of foreign work, in the study of renal microcirculation,