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[目的]总结分析5838例无症状人群上消化道癌内镜筛查结果。[方法]将高台县40~69岁的高危人群设定为上消化道癌筛查人群,采用整群抽样法进行抽样。对筛查人群进行内镜检查+碘染色及指示性活检,并对筛查结果进行统计分析。[结果]2011~2015年完成胃镜筛查病例5838例,共检出高级别上皮内瘤变及癌140例,检出率为2.40%,其中食管癌检出率为0.98%(57例),贲门癌为0.57%(33例),胃癌(非贲门)为0.86%(50例)。早期病例94例,早诊率为67.14%。应随访例数162例,实际随访105例,随访率为63.64%。随访中新发现病例6例,6例全部为早期病例,随即全部进行治疗。随访早诊率为100%,随访治疗率为100%。[结论 ]内镜检查+碘染色加指示性活检能有效发现可干预的癌前病变及早期癌。提高筛查项目点团队的专业技术能力,加强对高危人群的随访、治疗以及癌症防治知识的宣传,是开展上消化道癌症早诊早治项目的关键。
[Objective] To summarize the results of endoscopy screening of upper gastrointestinal cancer in 5838 asymptomatic subjects. [Methods] The high risk population from 40 to 69 years old in Gaotai County was set as the upper gastrointestinal cancer screening population and sampled by cluster sampling method. The screening population endoscopy + iodine staining and biopsy, and the screening results for statistical analysis. [Results] 5838 cases of endoscopy were completed in 2011-2015. High grade intraepithelial neoplasia and 140 cases were detected, the detection rate was 2.40%. The detection rate of esophageal cancer was 0.98% (57 cases) Cardiac cancer was 0.57% (33 cases), gastric cancer (non cardia) was 0.86% (50 cases). 94 cases of early cases, the diagnosis rate was 67.14%. The number of cases should be followed up 162 cases, the actual follow-up of 105 cases, the follow-up rate was 63.64%. During the follow-up, 6 newly discovered cases and 6 cases were all early cases, all were treated immediately. The rate of early diagnosis and follow-up was 100% and the follow-up treatment rate was 100%. [Conclusion] Endoscopy + iodine staining plus indicative biopsy can effectively detect precancerous and precancerous lesions that may be involved. It is the key to carry out the project of early diagnosis and early diagnosis and treatment of upper digestive tract cancer to improve the professional and technical abilities of the team of the screening project and to strengthen the follow-up, treatment and knowledge of cancer prevention and treatment for the high-risk population.