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1993～ 1999年 ,用半乳糖氧化酶雪夫法 (Go- S)对 12 9例有直肠息肉及直肠症状的患者作直肠粘液样本的 T抗原检测 ,随后作纤维结肠镜检查 ,并均取活体组织送病理检查。结果表明 :78例大肠癌和 5 1例非癌患者的直肠粘液标本中 ,T抗原阳性率分别为 78.2 1%和 15 .6 9%。Go- S检测大肠癌肛管粘液 T抗原的敏感度为 78.2 1% ,特异性 84.31% ,准确性为80 .6 2 %。研究提示 ,Go- S方法简便易行、价廉 ,结果较易重复 ,有一定筛选、普查及预防大肠癌的应用价值。
From 1993 to 1999, 290 samples of patients with rectal polyps and rectal symptoms with rectal polyps were examined for T-antigen using the galactose oxidase method (Go-S), followed by colonoscopy, and live tissue was taken. Send a pathological examination. The results showed that the positive rate of T antigen was 78.21% and 15.6% in 78 cases of colorectal cancer and 51 cases of non-cancerous rectal mucous. The Go-S detection sensitivity of colorectal cancer mucosal T antigen was 78.2 1%, specificity was 84.31%, and accuracy was 80.62%. Research suggests that the Go-S method is simple, inexpensive, and easy to replicate. It has a certain value for screening, screening, and prevention of colorectal cancer.