外阴阴道念珠菌病是常见的由念珠菌引起的妇科感染性疾病,具体发病机制不明,可能与局部免疫功能异常有关。近年女性生殖道局部免疫防御机制的研究倍受重视,上皮细胞的先天性抗念珠菌作用受到了越来越多的关注。现对近年阴道黏膜的先天抗白色念珠菌机制的研究进展作一综述。 Vulvovaginal candidiasis is a common gynecological infection caused by Candida disease, the specific pathogenesis is unknown, may be related to local immune dysfunction. In recent years, the research on local immune defense mechanism of female genital tract has drawn much attention, and the congenital anti-candidal effect of epithelial cells has received more and more attention. In recent years, the progress of research on the mechanism of congenital Candida albicans in vaginal mucosa is reviewed.