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选取2013年4月~2016年7月期间我院收治的59例糖尿病合并急性脑梗死患者,将其分为DMCI组,再选取同时期62例急性脑梗死患者将其分为CI组,同时期100例健康人员将其分为HC组。采用MRS扫描仪检测三组受检人员的脑组织基底节区或梗塞灶处的肌酸(Cr)、胆碱化合物肌酸(Cho)/Cr、N-乙酰天门冬氨酸(NAA)/Cr和乳酸(Lac)/Cr水平。结果:三组人员的Cr水平、NAA/Cr、Cho/Cr、Lac/Cr水平比较差异有统计学意义(P<0.05),进一步两两比较发现,HC组的Cr水平、NAA/Cr、Cho/Cr水平显著高于DMCI组患侧和CI组患侧,Lac/Cr低于DMCI组患侧和CI组患侧,差异有统计学意义(P<0.05),而CI组患侧的Cr水平、NAA/Cr、Cho/Cr、Lac/Cr水平显著高于DMCI组患侧,差异有统计学意义(P<0.05)。结论:MRS为临床研究糖尿病合并急性脑梗死患者的病理变化提供了新的检测手段。
Fifty-nine patients with diabetes mellitus complicated with acute cerebral infarction admitted to our hospital from April 2013 to July 2016 were divided into two groups: DMCI group, 62 acute cerebral infarction patients at the same period, which were divided into CI group and the same period 100 healthy people will be divided into HC group. The contents of creatine (Cr), choline (Cho) / Cr, NAA / Cr in basal ganglia or infarct area in brain tissue of three groups were detected by MRS scanner. And lactic acid (Lac) / Cr levels. Results: The levels of Cr, NAA / Cr, Cho / Cr and Lac / Cr in the three groups were significantly different (P <0.05) / Cr levels were significantly higher in the ipsilateral and the CI group than those in the DMCI group, and Lac / Cr was lower than those in the ipsilateral and the CI group in the DMCI group (P <0.05) , NAA / Cr, Cho / Cr, Lac / Cr levels were significantly higher than those in the DMCI group, the difference was statistically significant (P <0.05). Conclusion: MRS provides a new detection method for the clinical study of pathological changes in patients with diabetes mellitus and acute cerebral infarction.