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目的:观察卡前列素氨丁三醇和米索前列醇对高危孕妇剖宫产术后产后出血的防治效果。方法:选取我院2013年6月-2014年6月收治的行剖宫产术分娩产妇104例,将其随机分为卡前列素氨丁三醇组和米索前列醇组,所有患者均行剖宫产术分娩,在此基础上分别采用卡前列素氨丁三醇肌注、米索前列醇塞肛治疗,比较两组患者产后出血情况与不良反应发生率。结果:卡前列素氨丁三醇组产后出血率、产后2 h出血量、24 h出血量均明显优于米索前列醇组,差异均具有统计学意义(P<0.05)。卡前列素氨丁三醇组不良反应发生率为7.41%,米索前列醇组不良反应发生率为13.36%,组间比较,差异具有统计学意义(P<0.05)。结论:卡前列素氨丁三醇防治高危孕妇剖宫产术后产后出血效果显著,可有效增强子宫收缩力,降低产后出血率,减少不良反应发生率。
Objective: To observe the effect of carboprost trometamol and misoprostol on postpartum hemorrhage after cesarean section in high-risk pregnant women. Methods: A total of 104 pregnant women delivered by cesarean section in our hospital from June 2013 to June 2014 were randomly divided into triprolidine group and misoprostol group, all patients were treated Caesarean delivery, on this basis, respectively, with carboprost trometamol intramuscular injection, misoprostol plug anal treatment, postpartum hemorrhage and adverse reactions in both groups were compared. Results: The rate of postpartum hemorrhage, the amount of hemorrhage 2 h postpartum and the amount of hemorrhage 24 h were significantly higher than those of misoprostol (P <0.05). Adverse effects of carboprost and tromethamine were 7.41% and 13.36%, respectively. There was significant difference between the two groups (P <0.05). CONCLUSION: The effect of carboprost trometamol in preventing postpartum hemorrhage after cesarean section in high-risk pregnant women is significant. It can effectively enhance uterine contractility, reduce the rate of postpartum hemorrhage and reduce the incidence of adverse reactions.