自1971年Combes等发现成人输血后肝炎病人伴有膜性肾小球肾炎,并在肾小球内证实有HB抗原的免疫复合体的沉积以来,乙型肝炎病毒与肾炎的关系受到重视。1980年松田氏在日本报告28例儿童,发病年龄2～14岁。有不同程度的蛋白尿、血尿或两者均有而无乙型肝炎病毒性肾病的特征。但半数以上有肾病综合征的表现。光学显微镜下所见最多的是膜性肾小球肾炎,其次为膜性增殖性,少数为增殖性和微小 Since 1971, Combes and other found that adult patients with hepatitis B after transfusion associated with membranous glomerulonephritis, and in the glomerular deposition of HB antigen antigen complex was confirmed, the hepatitis B virus and nephritis relationship attention. Matsuda 1980 in Japan reported 28 cases of children, the age of onset 2 to 14 years old. There are varying degrees of proteinuria, hematuria or both without the characteristics of hepatitis B virus nephropathy. However, more than half of the performance of nephrotic syndrome. Membrane glomerulonephritis was most observed under the light microscope, followed by membranous proliferative and a few proliferative and small