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目的观察血清NT-pro BNP的检测对于妊娠期高血压疾病眼底病变的临床意义。方法分别对妊娠期高血压、轻度子痫前期、重度子痫前期患者各60例常规检查眼底,同时检测血清NT-pro BNP,对比分析血清NT-pro BNP对于妊娠期高血压疾病眼底病变的影响。结果妊娠期高血压、轻度子痫前期眼底基本正常,血清NT-pro BNP在正常范围或稍高,差异无统计学意义(P>0.05);重度子痫前期眼底改变明显,血清NT-pro BNP升高显著,与妊娠期高血压和轻度子痫前期组差异有统计学意义(P<0.01)。结论妊娠期高血压疾病患者血清NT-pro BNP显著升高时,临床医生应关注患者眼底病变。
Objective To observe the clinical significance of detection of serum NT-pro BNP in fundus lesions of hypertensive disorder complicating pregnancy. Methods 60 cases of routine examination of fundus in pregnancy-induced hypertension, mild preeclampsia and severe preeclampsia were respectively examined for serum NT-pro BNP. Serum levels of NT-pro BNP were compared with those of retinopathy of hypertensive disorder complicating pregnancy influences. Results The gestational hypertension and mild preeclampsia were normal and the serum NT-pro BNP was in the normal range or slightly higher than that in the normal range (P> 0.05). The changes of fundus in severe preeclampsia and serum NT-pro BNP increased significantly, with gestational hypertension and mild preeclampsia difference was statistically significant (P <0.01). Conclusion Serum NT-pro BNP in patients with gestational hypertension is significantly increased, clinicians should pay attention to patients with fundus lesions.