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糜酶(chymase)是一种丝氨酸蛋白酶,能高效特异地将血管紧张素1(angiotensinl,Augl)转化为Aug!。在人心脏中75%以上的Augl形成酶活性不能被Ansl转换酶抑制剂抑制,而能被丝氨酸蛋白酶抑制剂抑制(主要为糜酶活性),糜酶在人心脏中可能起着重要的作用。为研究人心脏糜酶
Chymase is a serine protease that efficiently and specifically converts angiotensin 1 (Aug1) into Aug! . More than 75% of the Aug1-forming enzyme activity in the human heart can not be inhibited by the Ansl converting enzyme inhibitor but can be inhibited by a serine protease inhibitor (mainly chymase activity) which may play an important role in the human heart. For the study of human cardiac chymase