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血细胞生长因子(HGFs)和干细胞移植已用于对抗大剂量化疗后的骨髓毒性作用,同样的方法建议用于放疗,尤其是包括大量活跃骨髓的放疗,如全脑全脊髓(CSA)照射。但病人的选择显得非常重要。为此,作者回顾性分析了1965～1994年间Royal Marsden医院收治的210例中枢神经系统肿瘤患者的资料。所有病人都接受了兆伏X线CSA照射。全脑照射30～40Gy,原发灶平均剂量55Gy,脊髓剂量是30Gy,转移灶再加量5～10Gy。平均治疗时间为8
Hepatocyte growth factor (HGFs) and stem cell transplantation have been used to counter the bone marrow toxicity following high-dose chemotherapy. The same method is recommended for radiotherapy, especially radiation therapy that includes a large amount of active bone marrow, such as whole brain and spinal cord (CSA) irradiation. However, the choice of the patient is very important. To this end, the author retrospectively analyzed data from 210 patients with central nervous system tumors admitted to the Royal Marsden Hospital between 1965 and 1994. All patients received megavoltage X-ray CSA irradiation. The whole brain was irradiated with 30-40 Gy, the average dose of the primary tumor was 55 Gy, the dose of the spinal cord was 30 Gy, and the amount of metastasis was increased by 5-10 Gy. The average treatment time is 8