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目的 研究拟黑多刺蚁(Polychachisricina Regen)对S_(180)肿瘤细胞DNA合成的影响,探讨该蚁抗肿瘤作用机理。方法 采用体外同位素放免法测定。结果 该蚁对小鼠S_(180)肿瘤细胞DNA合成有明显抑制作用(P<0.05),随该蚁剂量的增加,抑制作用增强,抑瘤率可高达96.4％。结论 拟黑多刺蚁对S_(180)肿瘤细胞有直接杀伤作用。
Objective To study the effect of Polychachis ricina Regen on DNA synthesis of S_(180) tumor cells and explore the anti-tumor mechanism of the ants. Methods In vitro isotope radioimmunoassay method was used for the determination. Results The ant significantly inhibited the DNA synthesis of mouse S_180 tumor cells (P<0.05). With the increase of the dose of the ant, the inhibitory effect was enhanced and the tumor inhibition rate was as high as 96.4%. Conclusion The black spiky ants have a direct killing effect on S_(180) tumor cells.