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44%的外科重危病人可产生院内细菌性肺炎,并与病情有关。在内毒素及其它细胞因子的作用下,肺泡巨噬细胞、纤维母细胞以及内皮细胞可分泌白介素8(IL-8),这是一种很强的多核白细胞趋化剂和激活剂。为此对肺泡腔和支气管分泌物(BS)中IL-8的存在及其和医院内感染肺炎发生发展的关系进行了研究。对收住在监护病房中的复合性创伤病人(TRAUMA)、非创伤性外科急诊病人(NTE)、
Forty-four percent of surgical critically ill patients develop nosocomial bacterial pneumonia and are associated with the disease. In the role of endotoxin and other cytokines, alveolar macrophages, fibroblasts and endothelial cells can secrete interleukin 8 (IL-8), which is a strong multicellular leukocyte chemotactic and activator. To this end on the alveolar and bronchial secretions (BS) in the presence of IL-8 and its relationship with the occurrence and development of hospital-acquired pneumonia were studied. For TRAUMA, non-traumatic surgical emergency patients (NTEs) admitted to an intensive care unit,