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目的观察不同阶段给予不同营养支持对重型颅脑损伤患者的影响。方法将126例重型颅脑损伤患者随机分为观察组和对照组各63例。观察组于伤后24小时内给予肠内营养(EN)加肠外营养(PN),逐渐过渡到肠内营养(EN);对照组于伤后进行全肠外营养(PN),一周后过渡到肠内营养(EN)。观察两组并发症的发生率以及伤后24小时,和第7天的体重及血生化指标变化情况。结果营养支持期间并发症发生率,观察组与对照组比较有显著性差异(P﹤0.05);体重变化差异性不显著;血红蛋白、血清蛋白,血糖值变化有显著性差异(P﹤0.05);营养支持期间费用观察组少于对照组。结论重型颅脑损伤患者早期分阶段给予EN联合PN营养支持可以减少并发症的发生,有利于患者的康复,值得推广。
Objective To observe the different stages of giving different nutritional support for patients with severe craniocerebral injury. Methods 126 cases of severe traumatic brain injury were randomly divided into observation group and control group of 63 cases. The observation group was given enteral nutrition (EN) plus parenteral nutrition (PN) within 24 hours after injury, and gradually transitioned to enteral nutrition (EN). In the control group, total parenteral nutrition (PN) To enteral nutrition (EN). The incidence of complications and the changes of body weight and blood biochemical indexes 24 hours after injury and 7 days after injury were observed. Results The incidence of complications during the nutritional support period was significantly different between the observation group and the control group (P <0.05); the difference of body weight was not significant; the changes of hemoglobin, serum protein and blood glucose were significantly different (P <0.05); Cost-support during the observation group less than the control group. Conclusions The early stage of severe craniocerebral injury patients with EN combined with PN nutrition support can reduce the incidence of complications, which is good for the recovery of patients and worthy of promotion.