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基因表达系列分析(SAGE)技术不仅能够全面地分析特定组织或细胞内表达的基因,还可以比较不同组织在不同时间、空间条件下基因表达的差异,从而发现新基因。SAGE技术在肿瘤研究中的应用发展很快。本文综述了SAGE技术的原理、应用及其近年来的发近几年展与演变。
Gene expression analysis (SAGE) not only enables a comprehensive analysis of genes expressed in specific tissues or cells, but also allows for the discovery of new genes by comparing the differences in gene expression between different tissues in different temporal and spatial conditions. The application of SAGE technology in cancer research is developing rapidly. This article summarizes the principle of SAGE technology, its applications and recent developments and developments in recent years.