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目的:分析比较LBP检测、HR-HPV检测对宫颈病变的筛查效果,探讨两者在宫颈病变检测中的相关性。方法:回顾性分析我院妇科门诊就诊的892名患者进行LBP、HR-HPV、LBP+HR-HPV检测的结果,比较它们之间的优劣性。结果:892例患者中用LBP和HPV检测呈单项阳性的分别为185例和181例,各单项检出率为20.7%和20.3%,而上述结果中呈双项阳性的患者只有146例,检出率仅为16.4%;LBP联合HR-HPV检测呈阳性的为678例,检出率达到76.0%,两种方法检测率之间差异无统计学意义,P<0.05。结论:两种方法的检测结果以及异常程度和感染量之间均无相关性,而两种方法联合使用可显著提高检出率,更有利于宫颈病变早期预防。
OBJECTIVE: To analyze and compare the screening effect of LBP test and HR-HPV test on cervical lesions and to explore the correlation between them in the detection of cervical lesions. Methods: The results of LBP, HR-HPV, LBP + HR-HPV test were analyzed retrospectively in 892 patients in gynecology outpatient department of our hospital, and their advantages and disadvantages were compared. Results: Among the 892 patients, there were 185 cases and 181 cases detected by LBP and HPV respectively. The individual detection rates were 20.7% and 20.3% respectively. There were only 146 cases with double positive in the above results The positive rate of LBP combined with HR-HPV was 678 and the detection rate was 76.0%. There was no significant difference between the two methods (P <0.05). Conclusion: There is no correlation between the detection results of the two methods and the degree of abnormality and the amount of infection. However, the combination of the two methods can significantly improve the detection rate and is more conducive to the early prevention of cervical lesions.