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目的观察小牛血清去蛋白注射液联合甲钴胺治疗糖尿病周围神经病变的临床疗效。方法将140例DPN患者随机分为观察组和对照组。在饮食、运动,糖尿病教育等基础治疗之上,观察组用小牛血清去蛋白注射液滴注联合甲钴胺注射液治疗,配合口服降糖药或加胰岛素治疗控制血糖。对照组则用甲钴胺注射液配合口服降糖药或加胰岛素治疗控制血糖。疗程2周。观察治疗前后的症状改善情况。结果对照组总有效率为55.6%,显效率为16.7%;治疗组总有效率为88.2%,显效率为44.1%,两组间差异有显著性(P<0.01)。结论小牛血清去蛋白注射液联合甲钴胺注射液治疗糖尿病周围神经病变疗效确切,优于单纯甲钴胺治疗方案。
Objective To observe the clinical effect of deproteinization of bovine serum and mecobalamin in the treatment of diabetic peripheral neuropathy. Methods 140 patients with DPN were randomly divided into observation group and control group. In the diet, exercise, diabetes education and other basic treatment, the observation group with dexamethasone deintan injection mecobalamin infusion therapy, with oral hypoglycemic agents or insulin therapy to control blood sugar. The control group with methylcobalamin injection with oral hypoglycemic agents or insulin therapy to control blood sugar. Treatment for 2 weeks. Observation of symptoms before and after treatment to improve the situation. Results The total effective rate of the control group was 55.6%, the effective rate was 16.7%. The total effective rate of the treatment group was 88.2%, the effective rate was 44.1%. There was significant difference between the two groups (P <0.01). Conclusion The effect of deproteinised bovine serum and methylcobalamin injection on diabetic peripheral neuropathy is better than mecobalamin alone.