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在日本,乌头(Aconitum carmichaeli)经高压蒸煮炮制后,得到减弱毒性的加工品(TJ-3022)用于临床。本次采用反相HPLC法检测了TJ-3022中乌头酸的两种同分异构体顺-乌头酸(CAA)和反-乌头酸(TAA)的含量。
In Japan, Aconitum carmichaeli was processed by autoclaving to obtain a weakened processed product (TJ-3022) for clinical use. The reversed-phase HPLC method was used to determine the content of two isomeric forms of aconitic acid (CAA) and trans-aconitic acid (TAA) in TJ-3022.