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目的调查宁波地区综合性医院耐亚胺培南鲍氏不动杆菌(IRAB)的耐药谱及临床分布。方法采用VITEK-32全自动细菌鉴定药敏系统及纸片扩散法(K-B法)测定鲍氏不动杆菌对15种抗菌药物的敏感性。结果257株IRAB主要来源于下呼吸道标本,占74.3%;IRAB在临床病区分布居前3位依次为ICU、呼吸科、神经外科,257株IRAB对多黏菌素B均敏感,除对多黏菌素B、头孢哌酮/舒巴坦、米诺环素以外,其余12种抗菌药物均显示>85.0%耐药。结论调查结果表明,IRAB医院感染和多药耐药已十分严重,应严密检测和控制。
Objective To investigate the drug resistance spectrum and clinical distribution of Acinetobacter baumannii in Ningbo general hospital. Methods The sensitivity of 15 kinds of antibacterials to Acinetobacter baumannii was determined by VITEK-32 automatic bacterial identification system and K-B method. Results 257 strains of IRAB mainly came from the lower respiratory tract specimens, accounting for 74.3%. The top three IRABs in the clinical ward were ICU, respiratory department and neurosurgery, and 257 strains of IRAB were sensitive to polymyxin B, Colistin B, cefoperazone / sulbactam, minocycline other 12 kinds of antibacterials showed> 85.0% resistance. Conclusion The survey results show that IRAB hospital infection and multidrug resistance have been very serious and should be closely tested and controlled.