治疗糖尿病酮症酸中毒,过去采用大量胰岛素治疗,但存在一些问题:静注胰岛素半衰期为4～5分钟,25分钟后只有初始剂量的1/10以下;肌注时半衰期为4小时,但吸收慢,且大量肌注为今后的治疗带来了困难。近年来有人提出在胰岛素受体饱和状态下,可能发挥最大降血糖作用;再大剂量亦是多余的。S(?)nkson Treatment of diabetic ketoacidosis, the past a large number of insulin treatment, but there are some problems: intravenous insulin half-life of 4 to 5 minutes, 25 minutes after the initial dose of only 1/10 or less; intramuscular half-life of 4 hours, but the absorption Slow, and a large number of intramuscular injection for future treatment has brought difficulties. In recent years, it has been suggested that in the state of insulin receptor saturation, may be the maximum hypoglycemic effect; then the high dose is superfluous. S (?) Nkson