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本文应用放射免疫方法测定了63例健康末孕妇女及221例正常妊娠(6～42周)妇女血清铁蛋白浓度。未孕组为54.1±43.4μmol/L,早、中、晚期妊娠组分别为(M±SD)48.8±30.0μmol/L、46.0±33.4μmol/L及24.3±14.8μmol/L以血清铁蛋白28.8μmol/L为缺铁性贫血指标,早、中、晚期妊娠组血清铁蛋白低于26.8μmol/L者分别占2.8％、26.9％及58.8％。妊娠期血清铁蛋白与血红蛋白呈正相关。早、中期妊娠组低铁蛋白和低Hb发生率两者无显著差异;而晚期妊娠组低铁蛋白者占58.8％,低Hb占35.2万,两者有显著差异(t=2.01)。说明血清铁蛋白对妊娠期贫血的检查率明显高于Hb。本文对6例不同孕期铁蛋白的动态测定表明,妊娠中期以后即应给予铁剂以预防妊娠期缺铁性贫血的发生。
In this paper, the serum ferritin concentrations in 63 healthy pregnant women and 221 normal pregnant women (6 ~ 42 weeks) were determined by radioimmunoassay. 54.1 ± 43.4μmol / L in non-pregnant group, 48.8 ± 30.0μmol / L, 46.0 ± 33.4μmol / L and 24.3 ± 14.8μmol / L respectively in early, middle and late pregnant women with serum ferritin 28.8 μmol / L for iron deficiency anemia, early, middle and late pregnancy serum ferritin less than 26.8μmol / L accounted for 2.8%, 26.9% and 58.8% respectively. Gestational serum ferritin and hemoglobin were positively correlated. There was no significant difference in the incidence of hypoferritin and low Hb between early pregnancy and second trimester pregnancy. In late pregnancy, low ferritin accounted for 58.8% and low Hb accounted for 352,000, both of which were significantly different (t = 2.01). Description of serum ferritin examination of anemia during pregnancy was significantly higher than Hb. This article on 6 cases of different pregnancy dynamic determination of ferritin, that should be given after the second trimester of iron to prevent the occurrence of iron deficiency anemia during pregnancy.