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目的 观察异丙酚防治硬膜外阻滞下胰腺癌根治术内脏牵拉反应的效果。方法 选择胰腺癌根治术 40例 ,硬膜外阻滞成功后随机分为两组 :Ⅰ组 (哌 口替啶 +氟哌利多组 ) 2 0例 ,Ⅱ组 (异丙酚组 ) 2 0例 ,记录病人牵拉反应情况。结果 Ⅱ组对控制内脏牵拉反应总有效率达 96 .33 % ;Ⅰ组对控制内脏牵拉反应总有效率为 74.95 %。两组间差异有显著性 (P <0 .0 5 )。Ⅱ组 3例舌后坠 ,需提下颌保持气道畅通。结论 异丙酚可作为硬膜外阻滞下防治胰腺癌手术内脏牵拉反应的辅助用药 ,但须注意呼吸道的管理
Objective To observe the effects of propofol in prevention and treatment of visceral traction response in pancreatic cancer under epidural anesthesia. Methods 40 cases of radical pancreatic cancer were selected and randomly divided into two groups after epidural blockade: Group I (pipotianidine + droperidol group) 20 cases, Group II (propofol group) 20 cases Record the patient’s traction response. Results The total effective rate of the visceral traction response in group II was 96.33%. The total effective rate of traction control in group I was 74.95%. There was a significant difference between the two groups (P < 0.05). In Group II, 3 patients suffered from posterior tongue fall, and the lower jaw was required to keep the airway open. Conclusion Propofol can be used as an adjunctive drug for prevention of visceral traction response in pancreatic cancer under epidural anesthesia, but attention must be paid to the management of respiratory tract.