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近年来,到性传播性疾病(STD)诊所就诊的生殖器疱疹病人明显增加。尽管生殖器疱疹以往报道很多,但针对其临床特征、病毒分离和复发病人传播的可能性的研究则甚少。本文作者对148例(女69,男79)过去曾接受了无环鸟苷治疗的复发性生殖器疱疹病人,进行了2个月的观察,年龄均在19岁和19岁以上,1年内至少发作过6次。采用标准表格记录以往复发的频率、严重程度和治疗情况;传染源以及是否有其他被感染的性侣;每一病人对疱疹知识的了解等。观察期间不接受任何治疗,要求病人复发时返回诊所,采访病史,记录临床特征并采集标本进行病毒培养。症状分为0～3级(0=无,1=轻,2=中,3=重)。
In recent years, there has been a marked increase in genital herpes patients who visit clinics for sexually transmitted diseases (STDs). Although genital herpes has been reported many times in the past, little is known about the clinical features, possibility of virus isolation and recurrence of patients. The authors of this study randomized 148 patients (69, 79) with recurrent genital herpes treated with acyclovir for 2 months, both at 19 and 19 years of age with at least one episode within one year 6 times. A standardized form was used to document the frequency, severity and treatment of previous relapses; the source of infection and whether there were other infected couples; and knowledge of herpes in each patient. During the observation did not receive any treatment, requiring patients to return to the clinic when the recurrence, interview history, record the clinical features and collection of specimens for virus culture. Symptoms were divided into 0 ~ 3 (0 = no, 1 = light, 2 = medium, 3 = heavy).