褪黑素(melatonin,MT)是在1959年由皮肤病学专家Lerner首先从牛的松果体提取物中纯化出来的,随后有关其生理、药理作用的研究便取得了明显的进展。Reiter等[1]在叙利亚仓鼠的研究中,首次证实了松果体至少是与生殖生理功能有关的内分泌器官。此后的一系列研究证明,松果体和它分 Melatonin (MT) was first purified from the pineal extract of cattle by dermatologist Lerner in 1959, and subsequent studies on its physiological and pharmacological effects have been markedly advanced. Reiter et al [1] in the Syrian hamster study, for the first time confirmed that the pineal gland is at least one of the reproductive physiology related endocrine organs. Since then a series of studies have shown that pineal and its points