本实验就鼠疫菌和假结核菌对上皮细胞的侵袭力，不仅进行了定性试验，同时还做了定量测定，证实了它们二者对上皮细胞（Ｈｅｐ－Ⅱ）侵袭性具有显著性差异，还证实在该实验条件下，鼠疫菌不同质粒缺乏株，对上皮细胞侵袭性无明显差别。也证实了鼠疫菌与假结核菌及不同质粒缺失鼠疫菌之间细胞毒性作用差别，并不是全由质粒介导的，可能是多种因素相互作用的结果。 In this experiment, the invasiveness of Yersinia pestis and pseudotuberculosis to epithelial cells was not only qualitatively tested, but also quantitatively determined, which confirmed that both of them had significant differences in the invasiveness of epithelial cells (Hep-Ⅱ) Confirmed that in this experimental conditions, different strains of Yersinia pestis lack of strains, no significant difference in the invasiveness of epithelial cells. Also confirmed the plague bacteria and pseudotuberculosis and different plaque plasmid plague lack of cytotoxicity differences, not all plasmid-mediated, may be the result of a variety of factors.