论文部分内容阅读
[目的]探讨CO2激光治疗尖锐湿疣过程中所排放的烟雾是否有人类乳头瘤病毒（HPV DNA）存在,这些病毒的致病性如何。[方法]收集32例尖锐湿疣患者的烟尘标本共96份,距烧灼部位1cm处、3cm处、5cm处各32份;用PCR方法检测烟尘标本中的HPV DNA,观察其阳性率;用烟尘标本涂擦30只大白鼠的阴道、外阴粘膜,对有皮损的部位做病理切片及PCR检测。[结果]用CO2激光治疗尖锐湿疣的烟尘中,有HPV DNA存在,经大白鼠感染试验证实,有一定的致病性。[结论]用CO2激光治疗的烟尘中有 HPV DNA存在;烟尘中的HPV DNA有一定的致病性;排烟设备距烧灼部位1cm以下最为安全。
[Objective] To investigate whether the smoke emitted during the CO2 laser treatment of condyloma acuminata has the existence of human papillomavirus (HPV DNA) and the pathogenicity of these viruses. [Method] Totally 96 samples of 32 patients with condyloma acuminatum were collected, at a distance of 1cm, 3cm and 5cm from the cauterization site. The HPV DNA in soot samples were detected by PCR and the positive rate was observed. Rub the vulva and vulva mucosa of 30 rats and make the pathological sections and PCR test on the lesion. [Results] There was HPV DNA in the CO2 laser treatment of genital warts, which was confirmed by the rat infection test and had certain pathogenicity. [Conclusion] The presence of HPV DNA in smoke and dust treated with CO2 laser has certain pathogenicity in HPV DNA in smoke and dust; the safety of smoke exhaust device below 1cm from burning site is safe.