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目的了解引起药源性低血钠的药物种类。方法回顾分析吉林大学第四医院从2009年1月1日至2011年1月1日期间收治的26例药源性低血钠住院患者的临床资料。结果本研究男17例,女9例(1.89:1);年龄49～80岁;抗癌药物导致的药源性低血钠居首位,尤以顺铂居首。结论作为医生在选药前,首先应全面考虑用药物治疗的利和弊,要充分了解所采用药物是否能造成心、肝、肾和神经系统等重要器官的不良反应。一般认为用药的目的必须是对患者益多于害。
Objective To understand the types of drugs that cause drug-induced hyponatremia. Methods The clinical data of 26 hospitalized patients with drug-induced hyponatremia admitted to the Fourth Hospital of Jilin University from January 1, 2009 to January 1, 2011 were retrospectively analyzed. Results In this study, 17 males and 9 females (1.89: 1) were aged 49-80 years old. Drug-induced hyponatremia caused by anticancer drugs ranked first, especially cisplatin. Conclusion As a doctor before choosing drugs, we should first fully consider the advantages and disadvantages of drug treatment and fully understand whether the drugs used can cause adverse reactions of vital organs such as heart, liver, kidney and nervous system. It is generally believed that the purpose of medication must be more harm than good to the patient.