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目的分析并评价联合应用呼吸机与肺表面活性剂治疗新生儿呼吸窘迫综合征的临床疗效。方法将我院收治的74例机械通气治疗的NRDS患儿分成两组各37例,对照组采用呼吸机辅助进行治疗,观察组在上述治疗基础上给予固尔苏进行治疗,对两组治疗后的血气指标与临床疗效进行比较。结果治疗后观察组与对照组各指标相比出现显著改善(P<0.05),具有统计学意义;观察组的显效率以及总有效率均高于对照组,两组比较差异有统计学意义(P<0.05)。结论联合应用机械通气与肺表面活性剂可以有效改善NRDS患儿的肺通气及换气功能,值得临床广泛推广应用。
Objective To analyze and evaluate the clinical efficacy of combined use of ventilator and pulmonary surfactant in the treatment of neonatal respiratory distress syndrome. Methods Totally 74 cases of NRDS patients treated by mechanical ventilation were divided into two groups (37 cases). The control group was treated with ventilator-assisted therapy. The observation group was treated with Guer Su on the basis of the above treatment. After treatment, Blood gas index and clinical efficacy were compared. Results After treatment, the observation group and the control group showed significant improvement (P <0.05), with statistical significance; the markedly effective rate and the total effective rate in the observation group were higher than those in the control group, with significant difference between the two groups P <0.05). Conclusions Combined use of mechanical ventilation and pulmonary surfactant can effectively improve pulmonary ventilation and ventilatory function in children with NRDS, which deserves wide application in clinic.