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目的:探讨综合性ICU呼吸机相关性肺炎(VAP)的发生率,为医院感染的防治提供依据。方法:对我院ICU于2002年1月~2005年4月38例呼吸机相关性肺炎患者的发病时间、病原学检查进行分析。结果:呼吸机相关性肺炎的发病率为46.34%,病死率为47.4%,VAP的发生与机械通气时间相关,以革兰氏阴性菌感染为主,且药敏显示对常用抗生素耐药严重。结论:ICU呼吸机相关性肺炎的发生率高,病死率高,合理使用抗生素,严格无菌操作,尽量缩短机械通气时间,提高机体免疫力,有利于VAP的控制。
Objective: To investigate the incidence of comprehensive ICU ventilator-associated pneumonia (VAP) and provide evidence for the prevention and treatment of nosocomial infections. Methods: The ICU in our hospital from January 2002 to April 2005 38 cases of ventilator-associated pneumonia in patients with onset time and etiological examination were analyzed. Results: The incidence of ventilator-associated pneumonia was 46.34% and the mortality rate was 47.4%. The incidence of VAP was related to the duration of mechanical ventilation. Gram-negative bacteria were the main cause of infection, and the drug susceptibility showed serious resistance to commonly used antibiotics. Conclusion: The incidence of ventilator - associated pneumonia in intensive care unit is high, the mortality rate is high, antibiotics are used reasonably, and aseptic operation is strictly performed. The time of mechanical ventilation is shortened, the immunity of the body is improved, and the control of VAP is beneficial.