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近年的研究表明,消化性溃疡与幽门螺杆菌(Hp)感染有关,笔者采用兰索拉唑和痢特灵二联治疗Hp阳性十二指肠溃疡患者,同时与得乐冲剂、甲硝唑和阿莫西林三联疗法比较,探讨二联疗法根除Hp的可行性,报道如下。 对象和方法 1.对象:经内镜检查证实Hp阳性的活动期十二指肠溃疡52例,其中男48例,女4例;年龄18～72岁,平均年龄37.2±2.0岁。均无活动性出血、穿孔及幽门梗阻等并发症。2周内未服用过铋剂、抗生素和抑酸药物。无慢性肝、肾功能障碍及青霉素过敏史。将所有病例随机分为两组,观察组(30例):用兰索拉唑30mg,每天1次,痢特灵100mg,每天3次,连服4周;
In recent years, studies have shown that peptic ulcer and Helicobacter pylori (Hp) infection, the author of lansoprazole and furazolidone diphtheria Hp-positive duodenal ulcer patients, and Dele granules, metronidazole and Amoxicillin triple therapy compared to explore the feasibility of dual therapy to eradicate Hp, reported as follows. Subjects and methods 1. Subjects: Endoscopic examination confirmed Hp-positive active duodenal ulcer in 52 cases, 48 males and 4 females; aged 18 to 72 years, mean age 37.2 ± 2.0 years. No active bleeding, perforation and pyloric obstruction and other complications. 2 weeks have not taken bismuth, antibiotics and acid-suppressing drugs. No chronic liver, kidney dysfunction and penicillin allergy history. All cases were randomly divided into two groups, the observation group (30 cases): Lansoprazole 30mg, once daily, 100mg furazolidone 3 times daily for 4 weeks;