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为什么紫外线照射容易致癌?流行病学调查显示,紫外线照射和皮肤鳞状细胞癌之间有联系,但死亡率未见增加。皮肤基底细胞癌也与紫外线照射有关,受紫外线照射后其发生率为正常对照组的1倍。紫外线照射引起的皮肤癌与DNA中形成嘧啶二聚体有关。在正常情况下,细胞内有正常的DNA修复系统可以清楚这种嘧啶二聚体,但在着色性干皮病病人由于缺乏切除嘧啶二聚体的修
Why UV exposure is easy to cause cancer? Epidemiological survey showed that there is a relationship between ultraviolet radiation and skin squamous cell carcinoma, but no increase in mortality. Skin basal cell carcinoma is also related to ultraviolet radiation, the incidence of UV irradiation after the normal control group 1 times. Skin cancer caused by ultraviolet radiation is related to the formation of pyrimidine dimers in DNA. Under normal circumstances, the cells have a normal DNA repair system to clear this pyrimidine dimer, but in patients with xeroderma pigmentosum due to lack of removal of pyrimidine dimer repair