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目的:了解医院门诊质子泵抑制药(PPI)的使用情况,为促进临床提高合理用药水平提供依据。方法:随机抽取医院2008年4月～2009年5月每月两天门诊消化内科处方,对使用质子泵抑制药的患者性别、年龄、临床诊断及各类质子泵抑制药的使用频度,与其他药物的联用情况进行分析。结果:门诊雷贝拉唑使用最为广泛占62.6%。雷贝拉唑与兰索拉唑DUI值均大于1,其用法用量的合理性有待进一步加强。药物间的联用情况也基本合理,PPI的适应证与治疗疾病基本一致。结论:PPI的使用基本合理。
Objective: To understand the use of proton pump inhibitor (PPI) in hospital clinics and to provide basis for promoting clinical use of rational drug use. Methods: Randomized two days outpatient digestive medicine prescriptions from April 2008 to May 2009 were randomly selected. The gender, age, clinical diagnosis and frequency of use of various proton pump inhibitors in patients with proton pump inhibitors were compared with The combination of other drugs for analysis. Results: Out-patient rabeprazole was the most widely used in 62.6%. Rabeprazole and lansoprazole DUI values were greater than 1, the rationality of its usage and dosage needs to be further strengthened. The combination of drugs is also basically reasonable, PPI indications and treatment of disease is basically the same. Conclusion: The use of PPI is basically reasonable.