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曾提出尿中的各种成份,如β_2—微球蛋白、新喋呤、肾小管酶类、血栓(口恶)烷B_2、白细胞介素—2(IL—2)及可溶性IL-2受体,可作为早期诊断排异反应的标志物,但是没有一种物质已被证明具有良好的特异性或良好的预示值。排异危象还与尿蛋白排出增多有关。作者用6个月时间研究了16例肾同种移植接受者(平均年龄39岁),他们接受了基础免疫抑制药物,包括硫唑嘌呤(2mg/kg/日)、甲基强的松龙(0.25mg/kg/日)和OKT3抗体(5mg/日,1个月)。其
Various urinary components such as β 2-microglobulin, neopterin, tubular enzymes, thromboxane B 2, interleukin-2 (IL-2), and soluble IL-2 receptor have been proposed , Can be used as a marker for the early diagnosis of rejection, but none have been shown to have good specificity or good predictive value. Excretion crisis also associated with increased urinary protein excretion. In a six-month study of 16 renal allograft recipients (mean age 39 years), they received basic immunosuppressive drugs including azathioprine (2 mg / kg / day), methylprednisolone 0.25 mg / kg / day) and OKT3 antibody (5 mg / day for 1 month). its