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本文研制了维生素B_6胃内漂浮型缓释片剂HBS-B_6,以延长其在胃肠道的滞留时间,提高生物利用度。测得其体外溶出速率K_r=0.1144h~(-1),用r-闪烁照相术比较了锝(T_C~(99m))标记的HBS-B_6片与普通
In this paper, vitamin B_6 intragastric floating sustained-release tablets HBS-B_6 to prolong its residence time in the gastrointestinal tract and improve bioavailability. Measured in vitro dissolution rate K_r = 0.1144h ~ (-1), compared with r-scintigraphy technetium (T_C ~ (99m)) labeled HBS-B_6 tablets and ordinary