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为了揭示血清可溶性白细胞介素2受体（sIL－2R）在各类急慢性肝病的具体改变，并依其变化判断肝损害的程度。本研究采用单克隆与多克隆双抗体夹心酶联免疫吸附法测定了各类肝病的sIL－2R水平。结果示各组病例sIL－2R增高幅度不同，其中重症肝炎＞急性肝炎＞活动性肝硬化＞慢性活动性肝炎＞肝癌＞代偿性肝硬化＞慢性迁延性肝炎。结果提示，进行性肝损害病人的sIL－2R水平的变化可作为判定肝组织病变程度的指标之一。
In order to reveal the specific changes of serum soluble interleukin 2 receptor (sIL-2R) in various acute and chronic liver diseases, and to determine the extent of liver damage according to changes. In this study, monoclonal and polyclonal antibody sandwich ELISA was used to determine the level of sIL-2R in various liver diseases. The results showed that each group of patients with different increases in sIL-2R, including severe hepatitis> acute hepatitis> active cirrhosis> chronic active hepatitis> liver cancer> compensated cirrhosis> chronic persistent hepatitis. The results suggest that the changes of sIL-2R levels in patients with progressive liver damage may be used as one of the indicators to determine the degree of liver lesions.