急性心肌梗死是在易损斑块破裂基础上继发血栓形成并堵塞冠状动脉管腔所致。目前普遍认为导致急性心肌梗死的斑块绝大多数表现为轻、中度管腔狭窄,但近两年来此观点愈来愈受到质疑与挑战。现将近几年关于管腔狭窄严重程度与急性心肌梗死关系的研究进展进行综述。 Acute myocardial infarction is secondary to thrombosis secondary to vulnerable plaque rupture and occlusion of the coronary lumen. It is generally accepted that most of the plaques that cause acute myocardial infarction are mild and moderate stenosis, but this view has been increasingly questioned and challenged in the recent two years. Now in recent years on the severity of stenosis and acute myocardial infarction research advances are reviewed.