论文部分内容阅读
目的从遗传与优生学角度出发,探讨了不明原因的胚胎早期停止发育、反复自然流产或原发不孕不育(包括原发、继发闭经和严重少精子、无精子症)与染色体异常的关系。方法对800例不孕不育患者及其中538例流产患者的配偶进行了染色体核型分析。结果1338例中发现异常核型84例,异常率占6.28%。其中平衡易位携带者14例,染色体数目异常39例,结构异常31例。结论染色体异常可导致不孕不育。提示不孕不育与遗传因素密切相关。
OBJECTIVE From the perspective of genetics and eugenics, explore the relationship between early unexplained embryo development, recurrent spontaneous abortion or primary infertility (including primary, secondary amenorrhea and severe oligozoospermia, azoospermia) and chromosomal abnormalities relationship. Methods Karyotype analysis was performed on the spouses of 800 infertility patients and 538 abortion patients. Results In 1338 cases, 84 cases of abnormal karyotype were found, accounting for 6.28%. Among them, 14 were carriers of balanced translocation, 39 were abnormal in chromosome number, and 31 were abnormal in structure. Conclusion Chromosomal abnormalities can lead to infertility. Suggest that infertility and genetic factors are closely related.