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本文报告醋酸甲孕酮(Depo-Provera)对家兔生育力抑制的情况及其机理.研究采用19只成年雌性新西兰大白兔,其中4只皮下注射Depo-Provera 20mg,7只皮下注射Depo-Provera 50mg,前者于注射后40～65天,后者于注后15～83天与3只雄兔交配或以人工阴道取得的3只雄兔的精子人工授精,50mg组并给hCG,于交配或授精后一天处死,计数排卵点并取出输卵管,以2ml培养液冲洗,在解剖显微镜下检查冲洗液内卵子是否受精.结果表明皮下注射Depo-Provera 20mg后40～65天家兔排卵仍被抑制;而
This paper reports the inhibition of fertility and its mechanism in rabbits by Depo-Provera.Methods Nineteen female New Zealand white rabbits were injected subcutaneously with four doses of Depo-Provera 20 mg and seven were injected subcutaneously with Depo-Provera 50mg, the former 40 to 65 days after injection, the latter 15 to 83 days after injection mating with three male rabbits or artificial vaginal sperm 3 sows obtained artificial insemination, 50mg group and give hCG, after mating or insemination One day, the ovulation was counted and the oviduct was taken out, rinsed with 2ml of culture solution and the ovum was irrigated under a dissecting microscope.The results showed that the ovulation was still inhibited 40-60 days after the subcutaneous injection of Depo-Provera 20mg,