盐酸麻黄碱滴鼻液的含量测定，主要采用双相滴定法，结果可靠，但繁琐费时，不适合对产品中间体的控制和快速分析的要求，根据盐酸麻黄碱具有旋光性的特点[1]，我们用旋光法直接测定盐酸麻黄碱滴具液的含量，结果与双相滴定法比较，无显著差异，本法回收率高，变异系数小，重视 Determination of ephedrine hydrochloride nasal drops, the main use of two-phase titration, the results are reliable, but cumbersome and time-consuming, not suitable for the control of intermediates and rapid product analysis requirements, according to ephedrine hydrochloride has optical characteristics [1] , We measured the content of Ephedrine Hydrochloride solution by the optical rotation method. There was no significant difference between the results and the two-phase titration method. The method has high recovery rate and small coefficient of variation