Angew.Chem.Int.Ed.2017,56,4824~4828吡啶类化合物是最重要的六元杂环衍生物,广泛存在于功能分子、药物和天然产物中.因此,发展合成吡啶衍生物的新方法有着重要意义,传统上吡啶的合成(如Hantsch合成法等)一般采用官能化底物通过加成、缩合和取代反应 Angew.Chem.Int.Ed.2017,56,4824-4828 Pyridine compounds are the most important six-membered heterocyclic derivatives, which are widely found in functional molecules, drugs and natural products.Therefore, the development of novel pyridine derivatives Method is of great significance. Traditionally, the synthesis of pyridine (such as the Hantsch synthesis method, etc.) generally use functionalized substrates through addition, condensation and substitution reactions