本文报告４７例上尿路结石并发急性尿毒症的手术治疗，除５例病情危重先经皮肾穿刺造瘘外，其余均行急症手术取石解除梗阻，结果２例死于术后水电解质紊乱，１例因肾功能不全病人自动放弃治疗，４４例治愈，效果良好，强调手术从速从简，术中彻底解除梗阻是治疗的关键，且勿依赖透析，延误病情 This article reports 47 cases of upper urinary tract stones complicated by acute uremic surgery, in addition to 5 cases of critically ill percutaneous nephroureterectomy, the rest were emergency surgical stone removal obstruction, the results of 2 patients died of postoperative water and electrolyte imbalance, 1 case of patients with renal insufficiency due to give up treatment, 44 cases were cured, the effect is good, emphasizing the operation as soon as possible, intraoperative completely relieve the obstruction is the key to treatment, and do not rely on dialysis, delay the disease