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慢性肾功能衰竭是肾脏的排泄、内分泌及代谢三种基本功能出现异常而出现的氮质血症和尿毒症。氮质血症是因为血中堆积一定量的含氮的代谢产物,而尿毒症是氮质血症与临床症状结合的表现,一些肾脏病随着病情恶化,有效肾单位逐渐减少,肾小球滤过功能逐渐降低,当降至正常值的5%时,甲状腺素可升高,肾脏调节水电解质功能下降,肾小管吸收能力下降,而使血钙下降,血磷升高,
Chronic renal failure is excretion of the kidneys, endocrine and metabolic abnormalities appear three basic functions of azotemia and uremia. Azotemia is due to blood accumulation of a certain amount of nitrogen-containing metabolites, and uremia is the combination of azotemia and clinical symptoms, some of the kidney disease as the disease deteriorated, the effective nephron gradually decreased, glomerular Filtration function gradually decreased, when reduced to 5% of normal, thyroid hormone can be increased, the kidneys regulate water and electrolyte function decline, renal tubular capacity decreased, leaving the blood calcium, blood phosphorus increased,