目的探讨角膜塑型术治疗中、低度近视的疗效及安全性。方法用OK镜治疗90例 (180眼 )近视 ,按球镜屈光度分为3组。Ⅰ组 :≤ -3.00D(58眼 ) ;Ⅱ组 :-3.25～ -5.00D(84眼 ) ;Ⅲ组 :-5.25～ -7.00D(38眼 )。结果随访3个月 ,Ⅰ、Ⅱ、Ⅲ组中裸眼视力≥1.0者 ,分别为55眼 (94.8% ) ,76眼 (90.5 % ) ,8眼 (21.1 % ) ;剩余屈光度≤ -0.50D者 ,分别为56眼 (96.6 % ) ,78眼 (92.8 % ) ,10眼 (26.3 % )。结论角膜塑型术是治疗中、低度近视的一种非手术性技术 ,能安全、有效地降低近视度数。 Objective To investigate the efficacy and safety of orthokeratology in the treatment of moderate and low myopia. Methods 90 cases (180 eyes) myopia were treated with OK lens, and were divided into 3 groups according to the diopter of the spherical mirror. Group Ⅰ: ≤ -3.00D (58 eyes); Group Ⅱ: -3.25 ~ -5.00D (84 eyes); Group Ⅲ: -5.25 ~ -7.00D (38 eyes). Results After 3 months of follow-up, there were 55 eyes (94.8%), 76 eyes (90.5%) and 8 eyes (21.1%) with visual acuity ≥1.0 in group Ⅰ, Ⅱ and Ⅲ, 56 eyes (96.6%), 78 eyes (92.8%) and 10 eyes (26.3%) respectively. Conclusion Orthokeratology is a non-surgical technique for the treatment of moderate and low myopia, which can reduce myopia safely and effectively.