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为考核含前Ｓ蛋白乙肝血源疫苗的人群免疫效果，对９６８名ＨＢＶ标志阴性的少年人群以１０μｇ×３的免疫剂量及０、１、２月免疫程序进行接种。全程免疫后一月采血检测其抗－ＨＢｓ免疫应答。结果表明抗－ＨＢｓ阳性率达９６．６％。并对另２９１名抗－ＨＢｃ及ＨＣＶ阳性的少年人群以同样的剂量、同样的免疫程序进行免疫接种，免疫后抗－ＨＢｓ阳性率为９４．１６％，且有２３．９８％的人接种后抗－ＨＢｃ由接种前的阳性转为阴性，全部观察对象无一例检出ＨＢｓＡｇ和其它异常指标
In order to test the immune effect of population containing hepatitis B virus vaccine containing pre-S protein, 968 HBV-negative juvenile populations were vaccinated with an immunization dose of 10 μg × 3 and an immunization schedule of 0, 1, and 2 months. Anti-HBs immune response was detected by blood sampling one month after full immunization. The results showed that anti-HBs positive rate of 96.6%. The other 291 anti-HBc and HCV-positive juvenile population were immunized with the same dose and same immunization procedure. The positive rate of anti-HBs after immunization was 94.16% and 23.98% Anti-HBc from positive before vaccination turned negative, none of the observed objects detected HBsAg and other abnormal indicators