患者女,44岁。因左乳头肿胀、糜烂、结痂3年,于2008年3月就诊。患者于3年前发现左乳头鳞屑性红斑,伴有轻度瘙痒,搔抓摩擦后出现糜烂、浆液性渗出,经多种糖皮质激素药膏外用后,瘙痒有改善,但糜烂面不愈,并逐渐扩大,表面结痂、呈结节状增生。皮肤科检查:左乳头肿大,结节状增生,表面红褐色结痂 Female patient, 44 years old. Due to the left nipple swelling, erosion, scab 3 years, in March 2008 treatment. 3 years ago, patients found that the left nipple scaly erythema, accompanied by mild itching, scratching friction after erosion, serous exudation, after a variety of glucocorticoid ointment topical, itching has improved, but the erosion surface healing, And gradually expanded, the surface scab, nodular hyperplasia. Dermatology examination: left nipple enlargement, nodular hyperplasia, the surface reddish brown scab