患者,男性,24岁。高度浮肿、大量蛋白尿1年,住院后诊断为肾病综合征。给予大剂量强的松75mg/日口服,2个月后尿蛋白转阴,强的松渐减量至40mg/日。5个月后无诱因突感右下肢膝关节肿痛,体温上升持续40℃,投用抗生素治疗症状不缓解,拟诊为痛风性关节炎转入院。查体:体温40℃,柯兴氏体态,心肺正常,肝脾未及,右下肢皮肤红、肿、热、痛 Patient, male, 24 years old. High edema, a large amount of proteinuria for 1 year, diagnosed as nephrotic syndrome after hospitalization. Give large doses of prednisone 75mg / day orally, 2 months after the urine protein turned negative, the gradual reduction of prednisone to 40mg / day. After 5 months no incentive to suddenly felt the right lower extremity knee swelling and pain, body temperature continued to rise 40 ℃, the use of antibiotics to treat symptoms do not ease, gout arthritis admitted to hospital. Physical examination: body temperature 40 ℃, Cushing’s posture, normal heart and lung, liver and spleen not, the right lower extremity skin red, swollen, hot, pain