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目的观察加减羚角钩藤汤联合西药治疗子痫前期的疗效及对妊娠结局的影响。方法将50例子痫前期患者随机分成西药组24例和联合组26例,西药组给予安定片及硫酸镁注射液治疗,联合组在西药组基础上加用羚角钩藤汤,两组均用药至孕妇分娩或终止妊娠,观察两组新生儿体重、新生儿Apgar评分、延长孕周时间、产后出血量、提前终止妊娠情况及重度患者孕周<34周情况。结果联合组新生儿出生体重较西药组重(P<0.01),孕周明显延长(P<0.01),计划外终止妊娠例数以及重度患者孕周<34周者均较西药组少(P<0.05)。两组患者产后出血量及新生儿Apgar评分比较差异无统计学意义(P>0.05)。结论加减羚角钩藤汤联合西药对子痫前期患者可延长孕周、改善妊娠结局。
Objective To observe the curative effect of plus and minus gazelle decoction combined with western medicine on preeclampsia and its effect on pregnancy outcome. Methods Fifty patients with preeclampsia were randomly divided into 24 cases in western medicine group and 26 cases in combination group. Western medicine group was treated with diazepam and magnesium sulfate injection. The combined group was given rhizoma cassiae herb extract on the basis of Western medicine group. To the delivery of pregnant women or termination of pregnancy, two groups of neonatal weight, neonatal Apgar score, prolonged gestational age, postpartum hemorrhage, early termination of pregnancy and severe gestational age <34 weeks. Results Compared with the western medicine group, the birth weight of newborns in the combined group was heavier (P <0.01), the gestational age was significantly longer (P <0.01), the number of unplanned termination of pregnancy and severe pregnant women <34 weeks were less than those in western medicine group (P < 0.05). There was no significant difference in postpartum hemorrhage volume and neonatal Apgar score between the two groups (P> 0.05). Conclusions Adding gingseng gouteng decoction combined with western medicine can prolong gestational age and improve pregnancy outcome in patients with preeclampsia.